On top of Matt LeBlanc's MIA sitcom "Joey," it looks like his marriage is facing cancellation.

The sitcom star filed for divorce from his wife Melissa Thursday, March 30 in Los Angeles, report news sources. They've been separated since New Year's Day.

According to an NBC spokesperson, "The dissolution is amicable. They remain devoted parents and friends."

LeBlanc is seeking joint custody of their two-year-old daughter, Marina Pearl. Although she was born healthy, at 11 months she began having seizures, difficulty walking and trouble with her other motor skills. Marina has been undergoing tests for a neurological disorder.

LeBlanc, 38, wed Melissa "Missy" McKnight in May 2003 in Hawaii with "Friends" co-stars Jennifer Aniston, Courtney Cox Arquette and Lisa Kudrow attending the nuptials.

The actor is also a stepfather to Tyler and Jacquelyne from his wife's first marriage.

"Joey" returned to NBC for one hot second in March before being yanked once again after getting dismal ratings opposite "American Idol." There's no word on when, or if, "Joey" will be back on the schedule.